Damien Paul Bintley, 45, from Holywood in County Down, died following a two-vehicle crash on the Crossowen Road in Clogher. The collision happened at about 12:40 BST on Friday, when the white MG HS car he was driving collided with a Volvo lorry.
Police said the Northern Ireland Ambulance Service provided treatment to a number of people at the scene. The 45-year-old later died from his injuries a short time afterwards.
What has been said about the crash?
The crash is the second fatal collision to occur in County Tyrone in as many days, after a teenager died in a crash near Coalisland.
DUP assembly member Deborah Erskine said her "heartfelt sympathies" are with the man's family, friends and loved ones.
"I also think of all those affected by this tragic incident, including the emergency services who attended the scene," she said.
"This is heartbreaking news for our local community. I would ask everyone to keep the family in their thoughts and prayers in the days and weeks ahead."
The crash happened on the Crossowen Road in Clogher.
